Laboratory Research in Pediatric Neurosurgery
The pediatric neurosurgery research laboratory is under the direction of Dr. Mark Souweidane, who is currently investigating interstitial infusion for pediatric brain tumors.
About Interstitial Infusion
A major limitation in treating pediatric brain tumors has been the ability to achieve adequate levels of a therapeutic agent within the tumor, due to the presence of the blood brain barrier (BBB). A major advance in the field of neuro-oncology has been the introduction of local delivery schemes, which administer therapeutic molecules directly into the tumor. Interstitial infusion is a local delivery system that has been investigated in Dr. Mark Souweidane's laboratory as a potential form of therapy for children with inoperable brain tumors. See the Research Overview here.
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